세부내용
키워드: 전통발효식품, K-장류, 건강기능성, 암 대사, 소화계암, 눈건강.
학력
2017 The University of Tennessee, Knoxville, 식품영양학 박사
2011 서울대학교 식품영양학 석사
2009 전북대학교 식품영양학과 학사 (부전공: 경영학)
2011 서울대학교 식품영양학 석사
2009 전북대학교 식품영양학과 학사 (부전공: 경영학)
경력
2025.09-현재 전북대학교 식품영양학과 부교수
2021.09-2025.08 전북대학교 식품영양학과 조교수
2017-2021 Thomas Jefferson University (NCI-designated-Sidney Kimmel Cancer Center) 박사후 연구원
2011-2013 한국식품연구원 연구 인턴쉽 및 연구보조원
2021.09-2025.08 전북대학교 식품영양학과 조교수
2017-2021 Thomas Jefferson University (NCI-designated-Sidney Kimmel Cancer Center) 박사후 연구원
2011-2013 한국식품연구원 연구 인턴쉽 및 연구보조원
담당과목
기초영양학(Basal Nutrition), 고급영양학(Advanced Nutrition), 생애주기영양학(Nutrition Through the Life Cycle), 지역사회영양학(Community Nutrition), 영양학특론(Theory of Advanced Human Nutrition), 고급영양이론(Advanced Nutrition), 임상영양연구(Clinical Nutrition Research), 생활습관영양학특론(Advanced Life-Style Nutrition), 영양과 노화(Nutrition and Aging)
연구업적
1) 논문 (Publications)
1. Park, J. E., Oh, S. M., Baek, J. Y., Yang, H. J., Jeong, D. Y., Han,A, & Cha, Y. S. (2025). Cheonggukjang, a gut microbiota-modulating Korean fermented food, improves cholesterol and bile acid metabolism. Food & Nutrition Research.
2. Jin, J. B., Robinson, A., Soukup, T., Black, E., Hammer, S., Han, A& Bae, J. (2025). Metabolic and molecular regulation in skeletal muscle dysfunction and regeneration. Frontiers in Cell and Developmental Biology, 13, 1651553.
3. Oluwasanmi, O. A., Sin, S. I., Park, S. H., & Han,A. (2025). Supplementation of deep-sea mineral water improves the anti-cancer effects of tomato in colorectal cancer cells. Journal of Functional Foods, 130, 106914.
4. Han A, Choi YJ (2024) Comparison of Metabolic Syndrome (MetS) Risk and Nutritional Status According to Menopause Age and the Impact of Socioeconomic Status on MetS Prevalence in Postmenopausal Women: A Cross-Sectional Study Based on the 8th Korea National Health and Nutrition Examination Survey (KNHANES). Nutrients, 27;16(7):967.
5. Chua V, Lopez-Anton M, Mizue Terai, Ryota Tanaka, Baqai U, Purwin TJ, Haj JI, Waltrich FJ Jr, Trachtenberg I, Luo K, Tudi R, Jeon A, HanA, Chervoneva I, Davies MA, Aguirre-Ghiso JA, Sato T, Aplin AE (2024) Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. Science Signaling, 11;17(840):eadn8376.
6. Seo EB, Oh SM, HanA(2024) Gochujangsuppresses cell survival and changes reactive oxygen species metabolism in colorectal cancer cells. Food & Nutrition Research, 21;68.
7. Edward OC, Jeong DY, Yang HJ, HanA, Cha YS (2024) Doenjang Ameliorates Diet-Induced Hyperlipidemia and Hepatic Oxidative Damage by Improving Lipid Metabolism, Oxidative Stress, and Inflammation in ICR Mice. Foods, 10;13(10):1471.
8. Jeong IK, HanA, Jun JE, Hwang YC, Ahn KJ, Chung HY, Kang BS, Choung SY. (2024) A Compound Containing Aldehyde Dehydrogenase Relieves the Effects of Alcohol Consumption and Hangover Symptoms in Healthy Men: An Open-Labeled Comparative Study. Pharmaceuticals (Basel), 20;17(8):1087.
9. Park JE, HanA, Mun EG, Cha YS (2024) A traditional Korean fermented food, Gochujangexerts anti-hypertensive effects, regardless of its high salt content by regulating renin-angiotensin-aldosterone system in SD rats. Heliyon, 28;10(9):e30451.
10. Han A, Choi YJ (2024) A national cross-sectional study on breakfast skipping-related factors and comparison of nutritional status according to breakfast skipping in older adults based on the 8th Korea National Health and Nutrition Examination Survey (KNHANES, 2020). Journal of Nutrition Health & Aging, 28(9):100335.
11. Baqai U, Kurimchak AM, Trachtenberg IV, Purwin TJ, Haj JI, HanA, Luo K, Pachon NF, Jeon A, Chua V, Davies MA, Gutkind JS, Benovic JL, Duncan JS, Aplin AE (2023) Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma. Journal of Biological Chemistry, 299(12):105418.
12. Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE (2023) Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth. Cancers (Basel), 30;15(13):3451.
13. Lee EJ, Song J, Park CH, Mun EG, Wang J, HanA, Park JE, Cha YS (2023) Soy Sauce Lowers Body Weight and Fat Mass in High-Fat Diet-Induced Obese Rats. Journal of Medcinal Food, 26(11):858-867.
14. Edward OC, Lee EJ, HanA, Mun EG, Yang HJ, Kim JW, Cha YS (2023) Gochujang Consumption Prevents Metabolic Syndrome in a High-Fat Diet Induced Obese Mouse Model. Journal of Medicinal Food, 26(4):244-254
15. Lee EJ, Edward OC, Seo EB, Mun EG, Jeong SJ, Ha G, HanA, Cha YS. (2023) Gochujang Ameliorates Hepatic Inflammation by Improving Dysbiosis of Gut Microbiota in High-Fat Diet-Induced Obese Mice. Microorganisms, 31;11(4):911.
16. Kim, N. Y., Kim, K. A., Yang, H. J., Jeong, S. J., Han A, & Cha, Y. S. (2023). Comparison of the laxative effects of Korean Gochujang containing different microbiota on loperamide-induced constipation in ICR mice. Food & Function, 14(16), 7615-7630.
17. Woo H, HanA, Park JE, Cha YS (2023) Korean fermented soybean paste (Doenjang) has anti-obesity and anti-hypertensive effects via the renin-angiotensin system (RAS) in high-fat diet-induced obese rats. PLoS One, 20;18(10):e0291762.
18. Lee, H., Song, J., Chung, S., Cha, Y. S., & HanA. (2023). Gochujang elicits anti-obesity effects by increasing capsaicin-independent brown adipogenesis and thermogenesis in high-fat diet induced obese mice. Journal of Functional Foods, 111, 105886.
19. Han A, Chua V, Baqai U, Purwin TJ, Bechtel N, Hunter E, Tiago M, Seifert E, Speicher DW, Schug ZT, Harbour JW, Aplin AE (2022) Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma. Oncogene, 41(8):1129-1139.
20. Chua, V., Han,A., Bechtel, N., Purwin, T. J., Hunter, E., Liao, C., ... & Aplin, A. E. (2022). The AMP‐dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma. Pigment Cell & Melanoma Research, 35(1), 78-87.
21. Edward OC, Thomas SS, Cha KO, Jung HA, HanA, Cha YS (2022) Green perilla leaf extract ameliorates long-term oxidative stress induced by a high-fat diet in aging mice. Nutrition Research and Practice 16(5):549-564.
22. Han A, Park Y, Lee YK, Park SY, Park CY (2022) Position Statement: Vitamin D Intake to Prevent Osteoporosis and Fracture in Adults. Journal of Bone Metabolism, 29(4):205-215.
23. Han A, Schug, Z. T., & Aplin, A. E. (2021). Metabolic alterations and therapeutic opportunities in rare forms of melanoma. Trends in cancer, 7(8), 671-681.
24. Han A,Purwin, T. J., & Aplin, A. E. (2021). Roles of the BAP1 tumor suppressor in cell metabolism. Cancer research, 81(11), 2807-2814.
25. Han A,Purwin, T. J., Bechtel, N., Liao, C., Chua, V., Seifert, E., ... & Aplin, A. E. (2021). BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors. Oncogene, 40(3), 618-632.
26. Kim, D., HanA, & Park, Y. (2021). Association of dietary total antioxidant capacity with bone mass and osteoporosis risk in Korean Women: Analysis of the Korea national health and nutrition examination survey 2008–2011. Nutrients, 13(4), 1149.
27. Chua, V., Mattei, J., HanA, Johnston, L., LiPira, K., Selig, S. M., ... & Patel, S. P. (2021). The latest on uveal melanoma research and clinical trials: updates from the cure ocular melanoma (CURE OM) science meeting (2019).
28. Teh, J. L., Purwin, T. J., HanA, Chua, V., Patel, P., Baqai, U., ... & Aplin, A. E. (2020). Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma. Molecular cancer therapeutics, 19(8), 1719-1726.
29. Han A, Bennett, N., Ahmed, B., Whelan, J., & Donohoe, D. R. (2018). Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases. Oncotarget, 9(43), 27280.
30. MacDonald, A. F., Bettaieb, A., Donohoe, D. R., Alani, D. S., HanA, Zhao, Y., & Whelan, J. (2018). Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties. BMC Complementary and Alternative Medicine, 18, 1-13.
31. Han A, Won, S. B., & Kwon, Y. H. (2017). Different effects of maternal low-isoflavone soy protein and genistein consumption on hepatic lipid metabolism of 21-day-old male rat offspring. Nutrients, 9(9), 1039.
32. Won, S. B., HanA, & Kwon, Y. H. (2017). Maternal consumption of low-isoflavone soy protein isolate alters hepatic gene expression and liver development in rat offspring. The Journal of Nutritional Biochemistry, 42, 51-61.
33. Johnstone, M., Bennett, N., Standifer, C., Smith, A., HanA, Bettaieb, A., ... & Donohoe, D. R. (2017). Characterization of the pro‐inflammatory cytokine IL‐1β on butyrate oxidation in colorectal cancer cells. Journal of Cellular Biochemistry, 118(6), 1614-1621.
34. Han A, Bennett, N., MacDonald, A., Johnstone, M., Whelan, J., & Donohoe, D. R. (2016). Cellular metabolism and dose reveal carnitine‐dependent and‐independent mechanisms of butyrate oxidation in colorectal cancer cells. Journal of cellular physiology, 231(8), 1804-1813.
35. Burke, S. J., Stadler, K., Lu, D., Gleason, E., HanA, Donohoe, D. R., ... & Collier, J. J. (2015). IL-1β reciprocally regulates chemokine and insulin secretion in pancreatic β-cells via NF-κB. American journal of physiology-endocrinology and metabolism, 309(8), E715-E726.
36. Park, S. J., Park, J. H., HanA, Davaatseren, M., Kim, H. J., Kim, M. S., ... & Kwon, D. Y. (2015). Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3‐L1 cells via activation of AMP‐activated protein kinase. Cell Biochemistry and Function, 33(4), 220-225.
37. Donohoe, D. R., Holley, D., Collins, L. B., Montgomery, S. A., Whitmore, A. C., Hillhouse, A., HanA,... & Bultman, S. J. (2014). A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner. Cancer discovery, 4(12), 1387-1397.
38. Jung, G. Y., Won, S. B., Kim, J., Jeon, S., HanA, & Kwon, Y. H. (2013). Betaine alleviates hypertriglycemia and tau hyperphosphorylation in db/db mice. Toxicological Research, 29, 7-14.
1. Park, J. E., Oh, S. M., Baek, J. Y., Yang, H. J., Jeong, D. Y., Han,A, & Cha, Y. S. (2025). Cheonggukjang, a gut microbiota-modulating Korean fermented food, improves cholesterol and bile acid metabolism. Food & Nutrition Research.
2. Jin, J. B., Robinson, A., Soukup, T., Black, E., Hammer, S., Han, A& Bae, J. (2025). Metabolic and molecular regulation in skeletal muscle dysfunction and regeneration. Frontiers in Cell and Developmental Biology, 13, 1651553.
3. Oluwasanmi, O. A., Sin, S. I., Park, S. H., & Han,A. (2025). Supplementation of deep-sea mineral water improves the anti-cancer effects of tomato in colorectal cancer cells. Journal of Functional Foods, 130, 106914.
4. Han A, Choi YJ (2024) Comparison of Metabolic Syndrome (MetS) Risk and Nutritional Status According to Menopause Age and the Impact of Socioeconomic Status on MetS Prevalence in Postmenopausal Women: A Cross-Sectional Study Based on the 8th Korea National Health and Nutrition Examination Survey (KNHANES). Nutrients, 27;16(7):967.
5. Chua V, Lopez-Anton M, Mizue Terai, Ryota Tanaka, Baqai U, Purwin TJ, Haj JI, Waltrich FJ Jr, Trachtenberg I, Luo K, Tudi R, Jeon A, HanA, Chervoneva I, Davies MA, Aguirre-Ghiso JA, Sato T, Aplin AE (2024) Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. Science Signaling, 11;17(840):eadn8376.
6. Seo EB, Oh SM, HanA(2024) Gochujangsuppresses cell survival and changes reactive oxygen species metabolism in colorectal cancer cells. Food & Nutrition Research, 21;68.
7. Edward OC, Jeong DY, Yang HJ, HanA, Cha YS (2024) Doenjang Ameliorates Diet-Induced Hyperlipidemia and Hepatic Oxidative Damage by Improving Lipid Metabolism, Oxidative Stress, and Inflammation in ICR Mice. Foods, 10;13(10):1471.
8. Jeong IK, HanA, Jun JE, Hwang YC, Ahn KJ, Chung HY, Kang BS, Choung SY. (2024) A Compound Containing Aldehyde Dehydrogenase Relieves the Effects of Alcohol Consumption and Hangover Symptoms in Healthy Men: An Open-Labeled Comparative Study. Pharmaceuticals (Basel), 20;17(8):1087.
9. Park JE, HanA, Mun EG, Cha YS (2024) A traditional Korean fermented food, Gochujangexerts anti-hypertensive effects, regardless of its high salt content by regulating renin-angiotensin-aldosterone system in SD rats. Heliyon, 28;10(9):e30451.
10. Han A, Choi YJ (2024) A national cross-sectional study on breakfast skipping-related factors and comparison of nutritional status according to breakfast skipping in older adults based on the 8th Korea National Health and Nutrition Examination Survey (KNHANES, 2020). Journal of Nutrition Health & Aging, 28(9):100335.
11. Baqai U, Kurimchak AM, Trachtenberg IV, Purwin TJ, Haj JI, HanA, Luo K, Pachon NF, Jeon A, Chua V, Davies MA, Gutkind JS, Benovic JL, Duncan JS, Aplin AE (2023) Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma. Journal of Biological Chemistry, 299(12):105418.
12. Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE (2023) Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth. Cancers (Basel), 30;15(13):3451.
13. Lee EJ, Song J, Park CH, Mun EG, Wang J, HanA, Park JE, Cha YS (2023) Soy Sauce Lowers Body Weight and Fat Mass in High-Fat Diet-Induced Obese Rats. Journal of Medcinal Food, 26(11):858-867.
14. Edward OC, Lee EJ, HanA, Mun EG, Yang HJ, Kim JW, Cha YS (2023) Gochujang Consumption Prevents Metabolic Syndrome in a High-Fat Diet Induced Obese Mouse Model. Journal of Medicinal Food, 26(4):244-254
15. Lee EJ, Edward OC, Seo EB, Mun EG, Jeong SJ, Ha G, HanA, Cha YS. (2023) Gochujang Ameliorates Hepatic Inflammation by Improving Dysbiosis of Gut Microbiota in High-Fat Diet-Induced Obese Mice. Microorganisms, 31;11(4):911.
16. Kim, N. Y., Kim, K. A., Yang, H. J., Jeong, S. J., Han A, & Cha, Y. S. (2023). Comparison of the laxative effects of Korean Gochujang containing different microbiota on loperamide-induced constipation in ICR mice. Food & Function, 14(16), 7615-7630.
17. Woo H, HanA, Park JE, Cha YS (2023) Korean fermented soybean paste (Doenjang) has anti-obesity and anti-hypertensive effects via the renin-angiotensin system (RAS) in high-fat diet-induced obese rats. PLoS One, 20;18(10):e0291762.
18. Lee, H., Song, J., Chung, S., Cha, Y. S., & HanA. (2023). Gochujang elicits anti-obesity effects by increasing capsaicin-independent brown adipogenesis and thermogenesis in high-fat diet induced obese mice. Journal of Functional Foods, 111, 105886.
19. Han A, Chua V, Baqai U, Purwin TJ, Bechtel N, Hunter E, Tiago M, Seifert E, Speicher DW, Schug ZT, Harbour JW, Aplin AE (2022) Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma. Oncogene, 41(8):1129-1139.
20. Chua, V., Han,A., Bechtel, N., Purwin, T. J., Hunter, E., Liao, C., ... & Aplin, A. E. (2022). The AMP‐dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma. Pigment Cell & Melanoma Research, 35(1), 78-87.
21. Edward OC, Thomas SS, Cha KO, Jung HA, HanA, Cha YS (2022) Green perilla leaf extract ameliorates long-term oxidative stress induced by a high-fat diet in aging mice. Nutrition Research and Practice 16(5):549-564.
22. Han A, Park Y, Lee YK, Park SY, Park CY (2022) Position Statement: Vitamin D Intake to Prevent Osteoporosis and Fracture in Adults. Journal of Bone Metabolism, 29(4):205-215.
23. Han A, Schug, Z. T., & Aplin, A. E. (2021). Metabolic alterations and therapeutic opportunities in rare forms of melanoma. Trends in cancer, 7(8), 671-681.
24. Han A,Purwin, T. J., & Aplin, A. E. (2021). Roles of the BAP1 tumor suppressor in cell metabolism. Cancer research, 81(11), 2807-2814.
25. Han A,Purwin, T. J., Bechtel, N., Liao, C., Chua, V., Seifert, E., ... & Aplin, A. E. (2021). BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors. Oncogene, 40(3), 618-632.
26. Kim, D., HanA, & Park, Y. (2021). Association of dietary total antioxidant capacity with bone mass and osteoporosis risk in Korean Women: Analysis of the Korea national health and nutrition examination survey 2008–2011. Nutrients, 13(4), 1149.
27. Chua, V., Mattei, J., HanA, Johnston, L., LiPira, K., Selig, S. M., ... & Patel, S. P. (2021). The latest on uveal melanoma research and clinical trials: updates from the cure ocular melanoma (CURE OM) science meeting (2019).
28. Teh, J. L., Purwin, T. J., HanA, Chua, V., Patel, P., Baqai, U., ... & Aplin, A. E. (2020). Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma. Molecular cancer therapeutics, 19(8), 1719-1726.
29. Han A, Bennett, N., Ahmed, B., Whelan, J., & Donohoe, D. R. (2018). Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases. Oncotarget, 9(43), 27280.
30. MacDonald, A. F., Bettaieb, A., Donohoe, D. R., Alani, D. S., HanA, Zhao, Y., & Whelan, J. (2018). Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties. BMC Complementary and Alternative Medicine, 18, 1-13.
31. Han A, Won, S. B., & Kwon, Y. H. (2017). Different effects of maternal low-isoflavone soy protein and genistein consumption on hepatic lipid metabolism of 21-day-old male rat offspring. Nutrients, 9(9), 1039.
32. Won, S. B., HanA, & Kwon, Y. H. (2017). Maternal consumption of low-isoflavone soy protein isolate alters hepatic gene expression and liver development in rat offspring. The Journal of Nutritional Biochemistry, 42, 51-61.
33. Johnstone, M., Bennett, N., Standifer, C., Smith, A., HanA, Bettaieb, A., ... & Donohoe, D. R. (2017). Characterization of the pro‐inflammatory cytokine IL‐1β on butyrate oxidation in colorectal cancer cells. Journal of Cellular Biochemistry, 118(6), 1614-1621.
34. Han A, Bennett, N., MacDonald, A., Johnstone, M., Whelan, J., & Donohoe, D. R. (2016). Cellular metabolism and dose reveal carnitine‐dependent and‐independent mechanisms of butyrate oxidation in colorectal cancer cells. Journal of cellular physiology, 231(8), 1804-1813.
35. Burke, S. J., Stadler, K., Lu, D., Gleason, E., HanA, Donohoe, D. R., ... & Collier, J. J. (2015). IL-1β reciprocally regulates chemokine and insulin secretion in pancreatic β-cells via NF-κB. American journal of physiology-endocrinology and metabolism, 309(8), E715-E726.
36. Park, S. J., Park, J. H., HanA, Davaatseren, M., Kim, H. J., Kim, M. S., ... & Kwon, D. Y. (2015). Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3‐L1 cells via activation of AMP‐activated protein kinase. Cell Biochemistry and Function, 33(4), 220-225.
37. Donohoe, D. R., Holley, D., Collins, L. B., Montgomery, S. A., Whitmore, A. C., Hillhouse, A., HanA,... & Bultman, S. J. (2014). A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner. Cancer discovery, 4(12), 1387-1397.
38. Jung, G. Y., Won, S. B., Kim, J., Jeon, S., HanA, & Kwon, Y. H. (2013). Betaine alleviates hypertriglycemia and tau hyperphosphorylation in db/db mice. Toxicological Research, 29, 7-14.