Kim, Shang-Jin Photo
Kim, Shang-Jin
Major
Veterinary Pharmacology
Position
Professor
Email
abbasj@jbnu.ac.kr
Office
R303, The 2nd Veterinary Building, Jeonbuk National University Specialized Campus, 79 Gobong-ro, Iksan-si, Jeonbuk State, Republic of Korea

Detail Information

• Drug repositioning 


• Drug development for cardiovascular diseases, cancer, liver diseases, diabetes, etc


• Pharmacological actions of medicinal plants and plant-derived active substances


• Natural Products Drug Efficacy Verification and Toxicity Evaluation


• Ion homeostasis related to animal diseases and drugs

Interests

• PhD : Veterinary Pharmacology ; College of Veterinary Medicine, Jeonbuk National University, Korea

• MS : Veterinary Pharmacology ; College of Veterinary Medicine, Jeonbuk National University, Korea

• BSc : Veterinary Medicine ; College of Veterinary Medicine, Jeonbuk National University, Korea

Education

• Oct 2019-present : Full Professor (College of Veterinary Medicine, Jeonbuk National University, Korea)

• Nov 2018-Nov 2020 :Head (Department of Veterinary Medicine, College of Veterinary Medicine, Jeonbuk National University, Korea)

• Oct 2014-Sep 2019 : Associate Professor (College of Veterinary Medicine, Jeonbuk National University, Korea)

• Aug 2012-Sep 2014 : Assistant Professor (College of Veterinary Medicine, Jeonbuk National University, Korea)

• Aug 2010-Jul 2012 : Full time lecturer (College of Veterinary Medicine, Jeonbuk National University, Korea)

• Apr 2007-Jul 2010 : Research Associate (Dept of Physiology & Pharmacolgy), BHF (British Heart Foundation) funded

• Apr 2006-Mar 2007 : Research Professor (College of Veterinary Medicine, Jeonbuk National University, Korea), NRF (National Research Foundation of Korea) funded

• Apr 2005-Mar 2006 : Post-doctoral Researcher (College of Veterinary Medicine, Jeonbuk National University, Korea), NRF (National Research Foundation of Korea) funded

• Mar 2000-Sep 2001 : Teaching Assistant (College of Veterinary Medicine, Jeonbuk National University, Korea), the Minister of Education of Korea appointed

Career

• Yang DK, Tunglag T, Lee SJ, Kim SJ. Methyl Jasmonate-induced Increase in Intracellular Magnesium Promotes Apoptosis in Breast Cancer Cells. Anticancer Res. 2024;44(3):1087-1095.

• Ahmed MA, Adam GO, Yang DK, Tunglag T, Lee SJ, Kang HS, Kim JS, Kim SJ. Effect of Low-dose Indole-3-Butyric Acid on Hematological and Serum Biochemical Parameters against Thioacetamide-Induced Acute Hepatotoxicity in Rats. Pak Vet J. 2023;43(1):125-131.

• Makki HMM, Adam GO, Yang DK, Tunglag T, Lee SJ, Kim JS, Kim SJ*, Kang HS. Effects of Gibberellic Acid on Thioacetamide-Induced Acute Liver Toxicity in Sprague-Dawley Rats. Pak Vet J. 2022;42(4):481-486. *; co-corresponding author.

• Adam GO, Kim SJ, Egbuna C, Oh HG. Ethnopharmacological Properties of African Medicinal Plants for the Treatment of Neglected Tropical Diseases. 9(4):59-72.

• Lee HR, Adam GO, Kim SJ. Application of Patient-Specific Instrumentation in a Dog Model with Antebrachial Growth Deformity Using a 3-D Phantom Bone Model. Vet Sci. 2022 Mar 25;9(4):157.

• Lee HR, Adam GO, Yang DK, Lee SJ, Kim HS, Kim SJ. Canine disorder of sex differentiation. Pak Vet J. 2020;40(4):540-542.

• Lee HR, Adam GO, Yang DK, Tungalag T, Lee SJ, Kim JS, Kang HS, Kim SJ*, Kim NS. An Easy and Economical Way to Produce a Three-Dimensional Bone Phantom in a Dog with Antebrachial Deformities. Animals (Basel). 2020;10(9):1445. *; co-corresponding author.

• Yang DK, Lee SJ, Adam GO, Kim SJ. Aralia continentalis kitagawaExtract Attenuates the Fatigue Induced by Exhaustive Exercise through Inhibition of Oxidative Stress. Antioxidants. 2020;9(3):379.

• Lee HR, Adam GO, Lee SJ, Kim SJ. Balloon dilation with triamcinolone intralesional injection successfully treated rectal stricture in a three-month kitten. Korean J Vet Res. 2020;60(1):39-42.

• Adam GO, Kim GB, Lee SJ, Lee H, Kang HS, Kim SJ. Red Ginseng Reduces Inflammatory Response via Suppression MAPK/P38 Signaling and p65 Nuclear Proteins Translocation in Rats and Raw 264.7 Macrophage. Am J Chin Med. 2019;47(7):1589-1609.

• Adam GO, Kim GB, Lee SJ, Lee HR, Kim SJ, Kim JS, Kang HS. Ultraviolet-C haematogenous oxidation therapy of lipopolysaccharide-induced endotoxemia in a rabbit model: A biochemical study. Indian J Biochem Biophysi. 2019;56(6):445-454.

• Adam GO, Kim GB, Lee SJ, Lee HR, Kim SJ, Kang HS, Kim JS. Long-term oral intake of Panax ginseng improves hypomagnesemia, hyperlactatemia, base deficit, and metabolic acidosis in an alloxan-induced rabbit model. Iran J Basic Med Sci. 2019 Jun;22(6):703-709.

• Adam GO, Lee HR, Lee SJ, Kim SJ, Kim GB, Kang HS. Effects of acute lipopolysaccharide-induced toxemia model on some neglected blood parameters. Pol J Vet Sci. 2018 Dec;21(4):665-671.

• Yang DK, Kim SJ. Cucurbitacin I Protects H9c2 Cardiomyoblasts against H2O2-Induced Oxidative Stress via Protection of Mitochondrial Dysfunction. Oxidative Med Cel. Longev. 2018 Feb 25;2018:3016382. doi: 10.1155/2018/3016382. eCollection 2018.

• Lee MY, Yang DK, Kim SJ. Alterations of Mg2+ After Hemorrhagic Shock.Biol Trace Elem Res. 2017 Nov;180(1);120-126.

• Yang DK, Kim SJ. Desipramine induces apoptosis in hepatocellular carcinoma cells. Oncol Rep. 2017 Aug;38(2):1029-1034.

• Rahman M, Yang DK, Kim GB, Lee SJ, Kim SJ. Nigella sativa seed extract attenuates the fatigue induced by exhaustive swimming in rats. Biomed Rep. 2017 Apr;6(4):468-474.

• Kim SJ, Park SH, Sin HS, Jang SH, Lee SW, Kim SY, Kwon B, Yu KY, Kim SY, Yang DK. Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats. Nutrients. 2017 Mar 16;9(3). pii: E293.

• Adam GO, Rahman MM, Lee SJ, Kim GB, Kang HS, Kim JS, Kim SJ. Hepatoprotective effects of Nigella sativa seed extract against acetaminophen-induced oxidative stress. Asian Pac J Trop Med. 2016 Mar;9(3):217-222.

• Rahman MM, Kim SJ. Effects of dietary Nigella sativa seed supplementation on broiler productive performance, oxidative status and qualitative characteristics of thighs meat. Ital J Anim Sci.2016;15(2):241-247.

• Zhang H, Cannell MB, Kim SJ, Watson JJ, Norman R, Calaghan SC, Orchard CH, James AF. Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload. PLoS One.2015 Dec 29;10(12):e0144309. doi: 10.1371/journal.pone.0144309.

• Rahman MM, Lee SJ, Rahman MM, Yang DK, Alam MR, Kim SJ. An accidental fatal attack on domestic pigeons by honey bees in Bangladesh. J Vet Med Sci. 2015 Nov 25; 77(11):1489-1493.

• Go HK, Rahman MM, Kim GB, Na CS, Song CH, Kim JS, Kim SJ*,Kang HS. Antidiabetic Effects of Yam (Dioscorea batatas) and Its Active Constituent, Allantoin, in a Rat Model of Streptozotocin-Induced Diabetes. Nutrients.2015 Oct 15;7(10):8532-44. *; co-corresponding author.

• Jeong MH, Kim SJ*,Kang H, Park KW, Park WJ, Yang SY, Yang DK. Cucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF-β/Smads Signalings. PLoS One. 2015 Aug 21;10(8):e0136236. doi: 10.1371/journal.pone.0136236. *; co-first author.

• Choisy SC, Kim SJ, Hancox JC, Jones SA, James AF. Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats. Physiol Rep. 2015 Jan 27;3(1). pii: e12274. doi: 10.14814/phy2.12274.

• Mun AR, Lee SJ, Kim GB, Kang HS, Kim JS, Kim SJ. Fluoxetine-induced Apoptosis in Hepatocellular Carcinoma Cells. Anticancer Res.2013 Sep;33(9):3691-3697. (IF 2.0, cited 56)

• Kim SJ, Zhang H, Khaliulin I, Choisy SC, Bond R, Lin H, El Haou S, Milnes JT, Hancox JC, Suleiman MS, James AF. Activation of glibenclamide-sensitive ATP-sensitive K+ channels during β-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia. Circ Arrhythm Electrophysiol. 2012 Dec;5(6):1184-1192.

• Kim SJ, Kim KH, Kim SJ, Kang HS, Kim JS, Kim MH, Jo JK, Choi JB, Yang YS, Kang SJ, Kim GB. Effectiveness of antioxidant and membrane oxygenator in acute respiratory distress syndrome by endotoxin. Korean J Chem Eng.2012 Nov;29(11):1597-1603.

• Park HM, Kim SJ*, Kim JS, Kang HS. Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced apoptosis in hepatoma cells through mitochondrial signaling pathways. Food Chem Toxicol.2012 Aug;50(8):2736-2741. *; co-first author.

• Park HM, Kim SJ*, Mun AR, Go HK, Kim GB, Kim SZ, Jang SI, Lee SJ, Kim JS, Kang HS. Korean red ginseng and its primary ginsenosides inhibit ethanol-induced oxidative injury by suppression of the MAPK pathway in TIB-73 cells. J Ethnopharmacol. 2012 Jun;141(3):1071-1076.*; co-first author.

• Kim SJ, Choisy SC, Barman P, Zhang H, Hancox JC, Jones SA, James AF. Atrial remodeling and the substrate for atrial fibrillation in rat hearts with elevated afterload. Circ Arrhythm Electrophysiol. 2011 Oct;4(5):761-769.

• Kim SJ, Lee SJ, Kim JS, Kang HS. High extracellular [Mg2+]-induced increase in intracellular [Mg2+] and decrease in intracellular [Na+] are associated with activation of p38 MAP kinase and ERK2 in guinea-pig heart. Exp Physiol. 2008 Dec;93(12):1223-1232.

• Kang HS, Kim SJ, Lee MY, Jeon SH, Kim JS. The cardiovascular depression caused by bee venom in Sprague-Dawley rats associated with a decrease of developed pressure in the left ventricular and the ratio of ionized calcium/ionized magnesium. Am J Chin Med. 2008;36(3):505-516.

• Kim SJ, Kang HS, Lee MY, Lee SJ, Seol JW, Park SY, Kim IS, Kim NS, Kim SZ, Kwak YG, Kim JS. Ketamine-induced cardiac depression is associated with increase in [Mg2+]i and activation of p38 MAP kinase and ERK 1/2 in guinea pig. Biochem Biophys Res Commun. 2006 Oct;349(2):716-722.

• Kim SJ, Kang HS, Jeong CW, Park SY, Kim IS, Kim NS, Kim SZ, Kwak YG, Kim JS, Quamme GA. Immunosuppressants inhibit hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells. Biochem Biophys Res Commun. 2006 Mar;341(3):742-748.

• Kim SJ, Kang HS, Kang MS, Yu X, Park SY, Kim IS, Kim NS, Kim SZ, Kwak YG, Kim JS. alpha(1)-Agonists-induced Mg(2+) efflux is related to MAP kinase activation in the heart. Biochem Biophys Res Commun. 2005 Aug 12;333(4):1132-8.